(A) ionized drugs are likely to cross into the CSF than unionized drugs
(B) the higher the lipid solubility of a drug, the more likely it will cross into the CSF
(C) inflammation of the meninges improves the likelihood that drugs will cross the BBB as compared to an uninflamed state

(D) None of These

(A) production of a more water-soluble moiety that is more easily excreted
(B) a drug with a different pharmacological mechanism of action
(C) a new compound that may also possess pharmacologic activity
(D) a drug molecule that may undergo enterohepatic recirculation and reintroduction into the bloodstream

(A) Subcutaneous and intramuscular route
(B) Intravenous route
(C) Subcutaneous route
(D) Intradermal and subcutaneous route

(A) Inactive metabolite from an active drug
(B) Active metabolite from an active drug
(C) Active metabolite from an inactive drug
(D) Inactive metabolite from inactive drug

(A) Stomach
(B) Small intestine
(C) Oesophagus
(D) Large intestine

(A) 100% bioavailable
(B) Rapidly absorbed
(C) Undergoes the first-pass metabolism
(D) Rapidly excreted by renal

(A) Can cause a parallel shift to the right in a drug-response curve for agonist
(B)  Can be reversed by increasing dose of agonist
(C) Appear to decrease the potency of the agonist
(D) All of the above