(A) Lipid-soluble
(B) Non-ionized substances
(C) Hydrophobic substances
(D) Hydrophilic substances

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(A) Lipid-soluble
(B) Non-ionized substances
(C) Hydrophobic substances
(D) Hydrophilic substances
(a) Active transport (carrier-mediated diffusion)
(B) Filtration (aqueous diffusion)
(C) Endocytosis and exocytosis
(D) Passive diffusion (lipid diffusion) (✓)
(A) Pharmacological effects of drugs
(B) Unwanted effects of drugs
(C) Chemical structure of a medicinal agent
(D) Distribution of drugs in the organism
(A) The study of biological and therapeutic effects of drugs
(B) The study of absorption, distribution, metabolism and excretion of drugs
(C) The study of mechanisms of drug action
(D) The study of methods of new drug development002. What does “pharmacokinetics” include?
(A) 2-3 half-lives
(B) 4-5 half-lives
(C) 6-7 half-lives
(D) 8-10 half-lives
(A) ionized drugs are likely to cross into the CSF than unionized drugs
(B) the higher the lipid solubility of a drug, the more likely it will cross into the CSF
(C) inflammation of the meninges improves the likelihood that drugs will cross the BBB as compared to an uninflamed state
(D) None of These
(A) production of a more water-soluble moiety that is more easily excreted
(B) a drug with a different pharmacological mechanism of action
(C) a new compound that may also possess pharmacologic activity
(D) a drug molecule that may undergo enterohepatic recirculation and reintroduction into the bloodstream
(A) Subcutaneous and intramuscular route
(B) Intravenous route
(C) Subcutaneous route
(D) Intradermal and subcutaneous route
(A) Inactive metabolite from an active drug
(B) Active metabolite from an active drug
(C) Active metabolite from an inactive drug
(D) Inactive metabolite from inactive drug